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High-efficiency EGFR genotyping using cell-free DNA in bronchial washing fluid.

Yoshihiko MurataYumi NakajimaYukio SatoNobuyuki HizawaDaichi YamakawaDaisuke MatsubaraMasayuki NoguchiYuko Minami
Published in: Japanese journal of clinical oncology (2024)
Using supernatant of bronchial washing fluid samples, the detection rate of EGFR mutation was high, and EGFR mutations were detectable even when no tumor cells had been detectable by biopsy or cytology. Supernatant of bronchial washing fluid might be an effective sample source for EGFR mutation testing.
Keyphrases
  • small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • high efficiency
  • fine needle aspiration
  • ultrasound guided
  • genome wide
  • gene expression
  • quantum dots