Redefining the Multiple Sclerosis Severity Score (MSSS): The effect of sex and onset phenotype.
Yuan ZhouSuzi B ClaflinJim StankovichIngrid van der MeiSteve Simpson YapRichard H RoxburghTomas KalincikLeigh BlizzardAlessandra LugaresiRaed AlroughaniSeyed Aidin SajediHelmut ButzkuevenEugenio PucciDaniele LA SpitaleriFranco GranellaEdgardo CristianoBassem YamoutStella HughesRiadh GouiderJosé Luis Sánchez MenoyoJavier OlascoagaChris McGuiganCameron ShawAllan G KermodeKrisztian KasaTalal Al-HarbiAyse AltintasGuy LaureysYara Dadalti FragosoTodd A HardyTunde CsepanyCarmen-Adella SirbuDanny DecooAttila SasJose C Alvarez-CermeñoKarim KotkataJorge Millán-PascualBruce V TaylorPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2019)
The differences in the disability accrual rate between progressive- and relapsing-onset MS have a significant effect on MSSS. An onset-specific MSSS should be used when comparing the rate of disability progression among progressive-onset cases and for mixed cohorts.