Venlafaxine and O-desmethylvenlafaxine serum levels are positively associated with antidepressant response in elder depressed out-patients.
Domenico De DonatisStefano PorcelliGerald ZernigLaura MercoliniGiancarlo GiupponiAlessandro SerrettiAndreas ConcaVincenzo FlorioPublished in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2021)
This study strongly suggests that TDM could represent a more appropriate tool than the oral dosage to optimise the treatment with VEN. Specifically, highest efficacy might be achieved by titrating patients at SCVO levels around 400 ng/mL.