Association of uric acid with kidney function and albuminuria: the Uric Acid Right for heArt Health (URRAH) Project.
Elisa RussoFrancesca ViazziRoberto PontremoliCarlo Maria BarbagalloMichele BombelliEdoardo CasigliaArrigo Francesco Giuseppe CiceroMassimo CirilloPietro CirilloGiovambattista DesideriLanfranco D'EliaClaudio FerriFerruccio GallettiLoreto GesualdoCristina GiannattasioGuido IaccarinoGiovanna LeonciniFrancesca MallamaciAlessandro MalobertiStefano MasiAlessandro MengozziAlberto MazzaMaria Lorenza MuiesanPietro NazzaroPaolo PalatiniGianfranco ParatiMarcello RattazziGiulia RivasiMassimo SalvettiValérie TikhonoffGiuliano TocciAndrea UngarPaolo VerdecchiaAgostino VirdisMassimo VolpeGuido GrassiClaudio Borghinull nullPublished in: Journal of nephrology (2021)
The lower the eGFR the higher the prevalence of hyperuricemia and gout. In subjects with eGFR < 60 ml/min the occurrence of hyperuricemia is about 10 times higher than in those with eGFR > 90 ml/min. The percentage of individuals treated with allopurinol was below 2% when GFR was above 60 ml/min, it increased to 20% in the presence of CKD 3b and rose further to 35% in individuals with macroalbuminuria.