Soluble ST2 as a New Oxidative Stress and Inflammation Marker in Metabolic Syndrome.
Ignacio RoyEva JoverLara MatillaVirginia AlvarezAmaya Fernández-CelisMaite BeunzaElena EscribanoAlicia GainzaRafael SadabaNatalia Lopez-AndreésPublished in: International journal of environmental research and public health (2023)
Circulating levels of sST2 are associated with oxidative stress and inflammation burden and may underlie the pathological remodeling and dysfunction of the heart in MS patients. Our results suggest that sST2 elevation precedes diastolic dysfunction, emerging as an attractive biotarget in MS.
Keyphrases
- oxidative stress
- metabolic syndrome
- ejection fraction
- diabetic rats
- dna damage
- mass spectrometry
- ischemia reperfusion injury
- end stage renal disease
- induced apoptosis
- multiple sclerosis
- ms ms
- newly diagnosed
- heart failure
- blood pressure
- chronic kidney disease
- left ventricular
- cardiovascular disease
- peritoneal dialysis
- insulin resistance
- risk factors
- adipose tissue
- signaling pathway