Impact of the time to achieve viral control on the dynamics of circulating HIV-1 reservoir in vertically infected children with long-term sustained virological suppression: A longitudinal study.
Matías MoragasMaximiliano DistefanoDebora MecikovskySolange Arazi CaillaudCarolina CernadasRosa BolognaPaula C AulicinoAndrea ManganoPublished in: PloS one (2018)
These data highlight that achieving VS during the first 18 months of life limit the establishment of HIV-1 reservoirs, reinforcing the clinical benefit of very early effective therapy in children.