Group-based trajectory modeling of intracranial pressure in patients with acute brain injury: Results from multi-center ICUs, 2008-2019.
Fan YangChi PengLiwei PengPeng WangChao ChengWei ZuoLei ZhaoZhichao JinWeixin LiPublished in: CNS neuroscience & therapeutics (2022)
This study identified three ICP trajectories associated with elevated risk, three with reduced risks for mortality during ICU hospitalization. Notably, a fixed ICP threshold should not be applied to all kinds of patients. GBTM, a granular method for describing ICP evolution and their association with clinical outcomes, may add to the current knowledge in intracranial hypertension treatment.
Keyphrases
- brain injury
- end stage renal disease
- subarachnoid hemorrhage
- ejection fraction
- blood pressure
- newly diagnosed
- healthcare
- chronic kidney disease
- peritoneal dialysis
- intensive care unit
- prognostic factors
- cardiovascular events
- type diabetes
- coronary artery disease
- cerebral ischemia
- optic nerve
- cardiovascular disease
- combination therapy
- replacement therapy