Genetic polymorphism of HLA-DRB1 alleles in Mexican mestizo patients with abdominal aortic aneurysms.
Javier E Anaya-AyalaSusana Hernandez-DoñoMonica Escamilla-TilchJose Marquez-GarciaKemberly Hernandez-SoteloRodrigo Lozano-CoronaDaniela Ruiz-GomezJulio GranadosCarlos A HinojosaPublished in: BMC medical genetics (2019)
Our study confirmed increased frequencies of the alleles HLA-DRB1*01 and HLA-DRB1*16 and their association to the development of AAA in Mexican Mestizo patients. The utility of genetic testing may assist in identifying individuals at genetic risk for the development of this disease in different ethnic groups, who might benefit from earlier ultrasound screening and closer imaging surveillance.