High serum IgA levels in patients with IgG4-related disease (IgG4-RD) are associated with mild inflammation, sufficient disease-specific features, and favorable responses to treatments.

Shunsuke TsugeIchiro MizushimaMakoto HoritaHiroyuki KawaharaHajime SanadaMisaki YoshidaYoshinori TakahashiTakeshi ZoshimaRyo NishiokaSatoshi HaraYasunori SuzukiKiyoaki ItoMitsuhiro Kawano

Published in: Modern rheumatology (2023)

Some patients diagnosed with IgG4-RD have high serum IgA levels. These patients may form a subgroup, characterized by good response to glucocorticoids, less frequent relapse, mildly elevated serum CRP levels, and possible complications of autoimmune diseases.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
oxidative stress
clinical trial
risk factors
open label