Login / Signup

High Throughput and Computational Repurposing for Neglected Diseases.

Helen W HernandezMelinda SoeungKimberley M ZornNorah AshouraMelina MottinCarolina Horta AndradeConor R CaffreyJair Lage de Siqueira-NetoSean Ekins
Published in: Pharmaceutical research (2018)
In the space of a few years many groups have either performed experimental or computational repurposing high throughput screens against neglected diseases. These have identified compounds which in many cases are already approved drugs. Such approaches perhaps offer a more efficient way to develop treatments which are generally not a focus for global pharmaceutical companies because of the economics or the lack of a viable market. Other diseases could perhaps benefit from these repurposing approaches.
Keyphrases
  • high throughput
  • single cell
  • health insurance
  • gene expression
  • genome wide
  • dna methylation
  • drug administration
  • drug induced