microRNA-125a-3p is regulated by MyD88 in Legionella pneumophila infection and targets NTAN1.

Elisa JenthoMalena BoddenChristine SchulzAnna-Lena JungKerstin SeidelWilhelm BertramsWilhelm Bertrams

Published in: PloS one (2017)

Taken together, we characterized the miRNA regulation in L. pneumophila infection with regard to MyD88 signaling and identified NTAN1 as a target of miR-125a-3p. This finding unravels a yet unknown feature of Legionella-host cell interaction, potentially relevant for new treatment options.

Keyphrases

toll like receptor
single cell
machine learning
cell therapy
deep learning
stem cells
inflammatory response
neural network