Elevated plasma triglyceride concentration and risk of adverse clinical outcomes in 1.5 million people: a CALIBER linked electronic health record study.
Riyaz S PatelLaura PaseaHandrean SoranPaul DownieRichard JonesAroon D HingoraniDermot NeelySpiros DenaxasHarry HemingwayPublished in: Cardiovascular diabetology (2022)
We highlight an exponential association between severe hypertriglyceridaemia and risk of incident acute and chronic pancreatitis, new diabetes, and mortality, especially at younger ages, but not for myocardial infarction for which only moderate hypertriglyceridemia conferred risk.
Keyphrases
- electronic health record
- cardiovascular disease
- type diabetes
- clinical decision support
- liver failure
- adverse drug
- heart failure
- drug induced
- left ventricular
- cardiovascular events
- respiratory failure
- early onset
- risk factors
- high intensity
- adipose tissue
- skeletal muscle
- aortic dissection
- hepatitis b virus
- insulin resistance
- acute respiratory distress syndrome