TRAP5b and RANKL/OPG Predict Bone Pathology in Patients with Gaucher Disease.

Margarita M IvanovaJulia DaoLauren NollJacqueline FikryOzlem Goker-Alpan

Published in: Journal of clinical medicine (2021)

TRAP5b, RANKL, and RANKL/OPG elevation indicate osteoclast activation in GD. TRAP5b is a potential bone biomarker for GD with the ability to predict the progression of bone density abnormalities.

Keyphrases

bone loss
bone mineral density
soft tissue
nuclear factor
bone regeneration
postmenopausal women
immune response
body composition
climate change
smoking cessation