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Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis.

Emily B WolfDavid LiAndre J FernandezLindsay B GardnerCandido E RiveraEwa M WysokinskaMarwan E ShaikhHan W TunVivek RoyMuhamad Alhaj Moustafa
Published in: Journal of investigative medicine high impact case reports (2023)
Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications. We report a case of acquired FVII deficiency in a patient with recurrent chronic myeloid leukemia in blast crisis who developed bilateral retinal hemorrhages. The coagulopathy was corrected with the initiation of chemotherapy and subsequent reduction in peripheral blast count.
Keyphrases
  • chronic myeloid leukemia
  • public health
  • replacement therapy
  • case report
  • optical coherence tomography
  • diabetic retinopathy
  • atrial fibrillation
  • squamous cell carcinoma
  • chemotherapy induced
  • smoking cessation