Marine fungal metabolite butyrolactone I prevents cognitive deficits by relieving inflammation and intestinal microbiota imbalance on aluminum trichloride-injured zebrafish.
Yingying NieJingming YangLongjian ZhouZhiyou YangJinyue LiangYayue LiuXiaoxiang MaZhongji QianPengzhi HongAllan V KalueffCai SongYi ZhangPublished in: Journal of neuroinflammation (2022)
The present findings suggest that BTL-I is a potential therapeutic agent for preventing CNS deficits caused by inflammation, neurotoxicity, and gut flora imbalance.