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Genome-wide association study to identify potential genetic modifiers in a canine model for Duchenne muscular dystrophy.

Candice L Brinkmeyer-LangfordCynthia Balog-AlvarezJames J CaiBrian W DavisJoe N Kornegay
Published in: BMC genomics (2016)
The results of this study enhance our understanding of GRMD pathology and represent a first step toward the characterization of GRMD modifiers that may be relevant to DMD pathology. Such modifiers are likely to be useful for DMD treatment development based on their relationships to GRMD phenotypes.
Keyphrases
  • duchenne muscular dystrophy
  • genome wide association study
  • muscular dystrophy
  • genome wide
  • human health
  • copy number
  • combination therapy
  • risk assessment