Relationship between the Plasma Proteome and Changes in Inflammatory Markers after Bariatric Surgery.

Helene A FachimZohaib IqbalJ Martin GibsonIvona Baricevic-JonesAmy E CampbellBethany Geary Akheel A Syed Anthony D WhettonHandrean SoranRachelle P DonnAdrian H Heald

Published in: Cells (2021)

Using SWATH-MS, we identified several proteins that are involved in the inflammatory response whose levels change in patients who achieve remission of T2DM after bariatric surgery in tandem with changes in IL6, TNFα and/or CRP. Future studies are needed to clarify the underlying mechanisms in how MBS decreases low-grade inflammation.

Keyphrases

low grade
inflammatory response
high grade
rheumatoid arthritis
oxidative stress
mass spectrometry
lipopolysaccharide induced
disease activity
multiple sclerosis
current status
lps induced
ms ms
toll like receptor
case control
ulcerative colitis
systemic lupus erythematosus
metabolic syndrome