Unexpected profile of sphingolipid contents in blood and bone marrow plasma collected from patients diagnosed with acute myeloid leukemia.
Marzena WątekBonita DurnaśTomasz WollnyMarcin PasiarskiStanisław GóźdźMichał MarzecAnna ChabowskaPrzemysław WolakMałgorzata Żendzian-PiotrowskaRobert BuckiPublished in: Lipids in health and disease (2017)
We hypothesize that changes in profile of sphingolipids concentration and some of their binding protein partners such as GSN in extracellular environment of blood and bone marrow cells in leukemic patients can be targeted to develop new AML treatment method(s).
Keyphrases
- acute myeloid leukemia
- bone marrow
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- mesenchymal stem cells
- binding protein
- peritoneal dialysis
- prognostic factors
- allogeneic hematopoietic stem cell transplantation
- patient reported outcomes
- acute lymphoblastic leukemia
- cell proliferation
- cell death