A molecular signature for the metabolic syndrome by urine metabolomics.

Chiara BruzzoneRubén Gil-RedondoMarisa SecoRocío BarragánLaura de la CruzClaire CannetHartmut SchäferFang FangTammo DiercksMaider BizkarguenagaBeatriz González-ValleAna LaínArantza Sanz-ParraOscar ColtellAnder López de LetonaManfred SpraulShelly C LuElisabetta BuguianesiNieves EmbadeQuentin M AnsteeDolores CorellaJosé M MatoÓscar Millet

Published in: Cardiovascular diabetology (2021)

Urine metabolomics, studied by NMR spectroscopy, unravelled a set of metabolites that concomitantly evolve with MetS progression, that were used to derive and validate a molecular definition of MetS and to discriminate the conditions that are in the interface between healthy individuals and the metabolic syndrome.

Keyphrases

metabolic syndrome
mass spectrometry
insulin resistance
uric acid
ms ms
single molecule
cardiovascular risk factors
cardiovascular disease
skeletal muscle