Effect of Gold Nanoparticle on 5-Fluorouracil-Induced Experimental Oral Mucositis in Hamsters.

Carmem Jane Ferreira VilarSusana Barbosa RibeiroAurigena Antunes de AraújoGerlane Coelho Bernardo GuerraRaimundo Fernandes de Araújo JúniorGerly Anne de Castro BritoRenata Ferreira Carvalho LeitãoDaniel de Lima PontesLuiz Henrique Da Silva GasparottoMaisie Mitchele Barbosa OliveiraAnderson Dias VianaWendy Marina Toscano Queiroz de MedeirosBreno Gustavo Porfírio BezerraCaroline Addison Carvalho Xavier de Medeiros

Published in: Pharmaceutics (2020)

AuNp (250 μg/kg) prevented 5-FU-induced OM in hamsters and improved the parameters of inflammation and oxidative stress.

Keyphrases

oxidative stress
diabetic rats
high glucose
dna damage
radiation induced
ischemia reperfusion injury
radiation therapy
induced apoptosis
signaling pathway