Cigarette smoking cessation, duration of smoking abstinence, and head and neck squamous cell carcinoma prognosis.
John J W LeeVijay KunaratnamChristina J H KimMartha PienkowskiKatrina HuenikenAxel SahovalerAndrew C L LamJoel C DaviesCatherine M BrownJohn R De AlmeidaShao Hui HuangJohn N WaldronAnna SpreaficoRayjean J HungWei XuDavid P GoldsteinGeoffrey LiuPublished in: Cancer (2023)
Smoking cessation before the time of diagnosis reduced overall mortality and cancer-specific mortality among patients with HNSCC, but no difference was observed in noncancer mortality. Long-term abstinence (>10 pack-years) had a significant OS and HNSCC-specific survival benefit.