Isolated Sporothrix schenckii Monoarthritis.
Aram BarbaryanWissam El AtrouniStefania BailucMatthew W JonesMaharshi BhaktaKhaldoun Haj MahmoudAibek E MirrakhimovPublished in: Case reports in infectious diseases (2018)
Sporothrix schenkii sensu lato is a rare cause of arthritis. Its course is indolent with lack of constitutional symptoms resulting in delayed presentation and diagnosis. It is a dimorphic fungus found ubiquitously in sphagnum moss, decaying vegetation, soil, and hay. Inoculation of dirt into the skin and soft tissues and, in rare instances, inhalation of aerosolized conidia from soil and plants can lead to infection. Subacute and chronic involvement of skin and subcutaneous tissues is the most common manifestation of sporotrichosis in immunocompetent hosts. In patients with underlying risk factors (HIV, alcoholism, diabetes mellitus, organ transplant patients, immunosuppressive medications, steroids, and malignancies), it can often have disseminated visceral, osteoarticular, meningeal, and pulmonary involvement. Sporothrical arthritis most commonly infects knee joint followed by hand and wrist joints. A culture of Sporothrix schenkii sensu lato is the gold standard for the diagnosis of sporotrichosis. Itraconazole is the drug of choice for osteoarticular sporotrichosis. We present a case of sporotrichal arthritis in a patient without skin or lymph node involvement who underwent treatment with itraconazole resulting in resolution of his symptoms.
Keyphrases
- rheumatoid arthritis
- lymph node
- risk factors
- soft tissue
- end stage renal disease
- wound healing
- gene expression
- case report
- chronic kidney disease
- ejection fraction
- newly diagnosed
- prognostic factors
- hiv positive
- human immunodeficiency virus
- hiv infected
- pulmonary hypertension
- patient reported outcomes
- peritoneal dialysis
- type diabetes
- climate change
- emergency department
- sleep quality
- early stage
- squamous cell carcinoma
- hiv testing
- adipose tissue
- physical activity
- radiation therapy
- metabolic syndrome
- glycemic control
- weight loss
- skeletal muscle