Can apelin play a role in the etiology of tinnitus?

Nuray Ensari Özer Erdem Gür Nilgün Gür Ömer Tarık Selçuk Levent Renda Mustafa Deniz Yılmaz Mehmet Türker Öztürk Yeşim Çekİn

Published in: Turkish journal of medical sciences (2019)

In our study, we found a negative correlation between apelin and tinnitus severity. Thus, apelin may play a role in the pathophysiology of idiopathic tinnitus, and may be prescribed during follow-up to reduce oxidative stress in the future. Further clinical studies on the effects of the apelin/APJ (apelin junction receptor) system and the effects of antioxidants in patients with inflammatory diseases are required.

Keyphrases

oxidative stress
hearing loss
dna damage
ischemia reperfusion injury
current status
induced apoptosis
heat stress