Maternal cold exposure induces distinct transcriptome changes in the placenta and fetal brown adipose tissue in mice.

Sujoy GhoshChul-Hong ParkJisu LeeNathan LeeRui ZhangClara HuesingDorien ReijndersJennifer SonesHeike MünzbergLeanne RedmanJi Suk Chang

Published in: BMC genomics (2021)

These findings provide evidence that environmental cold temperature sensed by the mother can modulate the transcriptome of placental and fetal BAT tissues. The ramifications of the observed gene expression changes warrant future investigation.

Keyphrases

gene expression
adipose tissue
dna methylation
rna seq
single cell
genome wide
insulin resistance
high fat diet induced
current status
high fat diet
birth weight
pregnancy outcomes
metabolic syndrome
risk assessment
climate change
preterm birth