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[An effect of ethylmethylhydroxypyridine succinate and ethylmethylhydroxypyridine malate on changes in mitochondrial function under conditions of focal cerebral ischemia].

Dmitryi Igorevich PozdnyakovD S ZolotykhA A Vihor
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2023)
The effect of malic acid and succinic acid salts of ethylmethylhydroxypyridine on the change in the redox and apoptosis-regulating function of mitochondria does not depend on the type of anion, whereas the change in the energy function of mitochondria is associated with the salt residue included in the drug structure and its dosage.
Keyphrases
  • cerebral ischemia
  • cell death
  • subarachnoid hemorrhage
  • blood brain barrier
  • ionic liquid
  • brain injury
  • oxidative stress
  • endoplasmic reticulum
  • cell cycle arrest
  • emergency department
  • electronic health record