Risk factors for bloodstream infections due to carbapenem-resistant Enterobacterales: a nested case-control-control study.
Hongyu ZhouNiccolò BuettiSalvador Pérez-GaleraJose Bravo-FerrerBelén Gutiérrez GutiérrezMaría Paniagua-GarcíaJan FeifelJulien SauserTomi KostyanevRafael CantónLionel K TanDimitris BasoulisVicente PintadoEmmanuel RoilidesGorana DragovacJulian Torre-CisnerosDeana MediçMurat AkovaHerman GoossensMarc BontenStephan HarbarthJesús Rodríguez-BañoJean-François Timsitnull nullPublished in: The Journal of antimicrobial chemotherapy (2024)
Evidence of previous CRE colonization/infection was a major risk factor for carbapenem resistance among Enterobacterales BSI. Compared with uninfected patients, evidence of previous MDRO colonization/infection and healthcare exposure were important risk factors for CRE BSI. Targeted screening, infection prevention and antimicrobial stewardship should focus on these high-risk patients.