Utility of the BioFire ® FilmArray ® Pneumonia Panel plus assay for syndromic testing of lower respiratory tract infections in a low/middle-income setting.
M Van Der WesthuyzenNazlee SamodienAdrian John BrinkC MoodleyPublished in: JAC-antimicrobial resistance (2023)
The FA-PP increased the number of positive samples with typical bacteria, but the semi-quantitative reporting algorithm does not describe the correlation between the different bin values and colonization versus infection. This complicates result interpretation and may lead to inappropriate antimicrobial treatment. This study highlights the potential positive impact of rapid molecular assays for routine care in lower-income settings, but also underscores the interpretive challenges associated with these tests.
Keyphrases
- respiratory tract
- high throughput
- physical activity
- healthcare
- mental health
- palliative care
- machine learning
- staphylococcus aureus
- high resolution
- deep learning
- intellectual disability
- quality improvement
- adverse drug
- intensive care unit
- human health
- climate change
- autism spectrum disorder
- mass spectrometry
- chronic pain
- affordable care act
- community acquired pneumonia