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Atypical Teratoid Rhabdoid Tumor in a Newborn: Can IVF Be a Risk Factor?

Turkay RzayevKübra Gökçe TezelSafak GucyetmezSuheyla BozkurtAdnan DagcinarGulnur TokucAkan YamanHulya Selva BilgenEren Ozek
Published in: Fetal and pediatric pathology (2021)
In recent years, with the widespread use of assisted reproductive technologies, questions have arisen regarding the possible relationship between these infertile parents with assisted conception procedures and childhood cancers. Case report: We present a 23-day-old newborn conceived by in vitro fertilization (IVF) with a 53 × 46 × 38 mm intracranial mass detected by magnetic resonance imaging on the 15th postnatal day. The mass, removed on 23rd postnatal day, was an Atypical Teratoid Rhabdoid Tumor (ATRT), WHO grade 4. Conclusions: As far as we know, this is the only neonatally detected ATRT. Further studies are needed to investigate whether there is a causal relationship between IVF and childhood cancers.
Keyphrases
  • magnetic resonance imaging
  • case report
  • pregnancy outcomes
  • preterm infants
  • childhood cancer
  • risk factors
  • type diabetes
  • pregnant women
  • metabolic syndrome
  • magnetic resonance
  • contrast enhanced
  • case control