The Impact of Polypill on Adherence and Cardiovascular Outcomes: A Comprehensive Systematic Review with Meta-Analysis.

Hamza Adel SalimBasel MusmarMotaz SaifiMohammed AyyadMohammed RuziehJehad AzarZaher Nazzal

Published in: Current cardiology reviews (2024)

Polypills were found to significantly reduce SBP, DBP and MACE. An improvement in medication adherence was also observed among polypill users, which might be responsible for the significant reduction in SBP observed users. Future research might benefit from exploring a more personalized approach to the composition of polypills, which could reveal a more clinically significant impact of increased adherence on CVD outcomes.

Keyphrases

glycemic control
genome wide
current status
single cell
type diabetes
gene expression
insulin resistance
skeletal muscle
weight loss