Soluble vascular endothelial-cadherin in CSF after subarachnoid hemorrhage.
Hajime TakaseSherry Hsiang-Yi ChouGen HamanakaRyo OhtomoMohammad R IslamJong Woo LeeLiangge HsuJustin MathewEstefania Reyes-BricioKazuhide HayakawaChanghong XingMing Ming NingXiaoying WangKen AraiEng H LoJosephine LokPublished in: Neurology (2020)
These results support the existence of a novel pathway by which sVE-cadherin, released from injured endothelium after SAH, can shift microglia into a more proinflammatory phenotype and contribute to neuroinflammation and poor outcome in SAH.