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Efficacy and safety of adjuvant immunoadsorption in pemphigus vulgaris and pemphigus foliaceus (IA-Pem Study): a multicentre randomised controlled trial.

Nina van BeekRüdiger EmingAlexander ReussDetlef ZillikensMiklós SárdyClaudia GüntherDimitra KiritsiSandrine BenoitStefan BeissertRegine GläserHarald GollnickOrsolya N HorváthChristiane PfeifferMartin RöckenFranziska SchauerStephan SchremlKerstin SteinbrinkAlexander ZinkCarmen Schade-BrittingerMichael HertlEnno Schmidt
Published in: The British journal of dermatology (2023)
In this study, adjuvant IA did not show a shorter time to clinical remission but a corticosteroid-sparing effect. In patients with extensive PV/PF, post hoc analysis suggests that adjuvant IA may possibly lead to earlier remission, but potential adverse events must be carefully weighed against the expected benefits.
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