Circular RNA HECTD1 Mitigates Ulcerative Colitis by Promoting Enterocyte Autophagy Via miR-182-5p/HuR Axis.

Yan XuYuxi TianFujun LiYing WangJunwen YangHui GongXiaoping WanMiao Ouyang

Published in: Inflammatory bowel diseases (2021)

Overexpression of circHECTD1 alleviates UC by promoting HuR-dependent autophagy via miR-182-5p. This study highlights the therapeutic potential of circHECTD1 for UC and adds to the knowledge of circRNA in the pathogenesis of UC.

Keyphrases

ulcerative colitis
cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
binding protein
healthcare
cell proliferation
transcription factor
radiation induced