Lung function in relation to brain aging and cognitive transitions in older adults: A population-based cohort study.

Giulia GrandeYuanjing LiCaterina TrevisanDebora RizzutoGrégoria KalpouzosMozhu DingErika J LaukkaTom BellanderLaura FratiglioniChengxuan Qiu

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

Poor lung function increased the risk of dementia and mild cognitive impairment (MCI). Poor lung function accelerated the progression from MCI to dementia. Poor lung function was linked to brain microvascular damage and global brain atrophy.

Keyphrases

lung function
mild cognitive impairment
cognitive decline
cystic fibrosis
chronic obstructive pulmonary disease
air pollution
resting state
white matter
functional connectivity
cerebral ischemia
physical activity
multiple sclerosis
brain injury