Leptin-Melanocortin pathway variants and gastric emptying in patients with obesity.

Lizeth CifuentesWissam GhusnAlejandro CamposJoshua T BublitzMaria Daniela HurtadoJanet OlsonAndres Acosta

Published in: Neurogastroenterology and motility (2024)

Carriers of heterozygous variants in the Leptin-MC4R pathway had a delayed GE compared to noncarriers. These findings point the important relationship between the Leptin-MC4R pathway and gastric motility.

Keyphrases

copy number
metabolic syndrome
type diabetes
insulin resistance
early onset
gene expression
dna methylation
body mass index
adipose tissue
physical activity