Catalytic Decarboxylative Fluorosulfonylation Enabled by Energy-Transfer-Mediated Photocatalysis.

Zhi-Da ChenXiang ZhouJi-Tao YiHong-Juan DiaoQi-Long ChenGui Lu Jiang Weng

Published in: Organic letters (2022)

Sulfonyl fluorides are useful building blocks in a wide array of fields. Herein, we report a catalytic decarboxylative fluorosulfonylation approach for converting abundant aliphatic carboxylic acids to the corresponding sulfonyl fluorides. This transformation is enabled by simple preactivation as aldoxime esters and energy-transfer-mediated photocatalysis. This operationally simple method proceeds with high functional-group tolerance under mild and redox-neutral conditions.

Keyphrases

energy transfer
visible light
quantum dots
high resolution
high throughput
crystal structure
single cell
electron transfer