In vivo PET imaging of neuroinflammation in familial frontotemporal dementia.
Maura MalpettiTimothy RittmanPeter Simon JonesThomas Edmund CopeLuca PassamontiWilliam Richard Bevan-JonesKaralyn PattersonTim D FryerYoung T HongFranklin I AigbirhioJohn Tiernan O'BrienJames Benedict RowePublished in: Journal of neurology, neurosurgery, and psychiatry (2020)
This case series suggests that neuroinflammation is part of the pathophysiology of familial FTD, warranting further consideration of immunomodulatory therapies for disease modification and prevention.