Tumor Dynamic Model-Based Decision Support for Phase Ib/II Combination Studies: A Retrospective Assessment Based on Resampling of the Phase III Study IMpower150.
René BrunoMathilde MarchandKenta YoshidaPhyllis ChanHaocheng LiWei ZouFrancois MercierPascal ChanuBenjamin WuAnthony LeeChunze LiJin Yan JinMichael L MaitlandMartin ReckMark A SocinskiPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Model-based estimate of KG GMR is an exploratory endpoint that informs early clinical decisions for combination studies.