A nomogram based on TFE3 IHC results and clinical factors as a preliminary screening scheme for TFE3-rearranged renal cell carcinoma.

Pengju LiQuanhui XuMinyu ChenJiangquan ZhuYinghan WangMukhtar A MuminKangbo HuangZeying JiangHui LiangQiong DengZhu WangBing LiaoWenfang ChenYun CaoJiazheng CaoJunghang Luo

Published in: Cancer medicine (2024)

TFE3 IHC has high accuracy in the diagnosis of TFE3-rearranged RCC. Clinical information such as age and lymph node metastasis are independent risk factors, which can be used as a supplement to the results of TFE3 IHC. This study confirms the value of IHC in the diagnosis of TFE3-rearranged RCC. The accuracy of the diagnosis can be improved by incorporating IHC with other clinical risk factors.

Keyphrases

lymph node metastasis
risk factors
renal cell carcinoma
squamous cell carcinoma
healthcare
papillary thyroid