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PINK1-mediated mitophagy induction protects against preeclampsia by decreasing ROS and trophoblast pyroptosis.
Yanan Sun
Dan Lv
Yin Xie
Heze Xu
Xuanxuan Li
Fanfan Li
Yao Fan
Xiaolei Zhang
Yanling Zhang
Suhua Chen
Mengzhou He
Dongrui Deng
Published in:
Placenta (2023)
This study demonstrated that PINK1-mediated mitophagy might played a protective role in PE by reducing ROS and trophoblast pyroptosis.
Keyphrases
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nlrp inflammasome
cell death
dna damage
reactive oxygen species