Clinical Burkholderia pseudomallei isolates from north Queensland carry diverse bimABm genes that are associated with central nervous system disease and are phylogenomically distinct from other Australian strains.
Delaney BurnardMichelle J BauerCaitlin FalconerIan GassiepRobert E NortonDavid L PatersonPatrick N A HarrisPublished in: PLoS neglected tropical diseases (2022)
The findings of this research have provided clinically relevant genomic data of B. pseudomallei in Queensland and suggest that the bimABm variant may enable risk stratification for the development CNS complications and be a potential therapeutic target.