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Comparison of Microdilution Method with Agar Dilution Method for Antibiotic Susceptibility Test of Neisseria gonorrhoeae.

Shao-Chun ChenJing-Wei LiuXing-Zhong WuWen-Ling CaoFeng WangJin-Mei HuangYan HanXiao-Yu ZhuBang-Yong ZhuQuan GanXiao-Zheng TangXing ShenXiao-Lin QinYu-Qi YuHe-Ping ZhengYue-Ping Yin
Published in: Infection and drug resistance (2020)
We conclude that the MD method might be an alternative for clinical AST of N. gonorrhoeae in China. In particular, MD method has the potency of accurate differentiation of isolates resistant to ceftriaxone or azithromycin, which were empirically recommended for gonococcal treatment, but its quality remained suboptimal, and further improvement is needed for clinical use.
Keyphrases
  • high resolution
  • liquid chromatography tandem mass spectrometry
  • quality improvement
  • combination therapy