Spinal Excitability in Patients with Painful Chronic Pancreatitis.

Cecilie Siggaard Knoph Rasmus Wiberg Nedergaard Søren Schou Olesen Louise Kuhlmann Asbjørn Mohr Drewes

Published in: Journal of pain research (2023)

We demonstrated somatic hyperalgesia in patients with painful CP associated with spinal hyperexcitability. This highlights that management should be directed at central mechanisms using, eg, gabapentinoids or serotonin-noradrenaline reuptake inhibitors.

Keyphrases

spinal cord
neuropathic pain
copy number
spinal cord injury
gene expression
dna methylation