Differences in the Circulating Proteome in Individuals with versus without Sickle Cell Trait.

Yanwei CaiNora FranceschiniAditya L Surapaneni Melanie E GarrettUsman A TahirLi Hsu Marilyn J Telen Bing YuHua TangYun Li Simin Liu Robert E Gerszten Josef Coresh Jo Ann E Manson Genevieve L WojcikCharles KooperbergPaul L Auer Matthew W Foster Morgan E Grams Allison Ashley KochLaura M RaffieldAlex P Reiner

Published in: Clinical journal of the American Society of Nephrology : CJASN (2023)

We identified and replicated the association of sickle cell trait with a number of plasma proteins related to hemolysis, kidney injury, and inflammation.

Keyphrases

genome wide
oxidative stress
dna methylation
red blood cell
gene expression