Progressive loss of hepatocyte nuclear factor 4 alpha activity in chronic liver diseases in humans.

Sumedha GunewardenaIan HuckChad WaleskyDakota R RobartsSteven WeinmanUdayan Apte

Published in: Hepatology (Baltimore, Md.) (2022)

In conclusion, these data indicate that loss of HNF4α function is a common event in the pathogenesis of CLDs leading to HCC and is important from both diagnostic and therapeutic standpoints.

Keyphrases

nuclear factor
toll like receptor
multiple sclerosis
electronic health record
liver injury
big data
inflammatory response
drug induced
immune response
machine learning
artificial intelligence