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Revisiting dezocine for opioid use disorder: A narrative review of its potential abuse liability.

Gordon A BarrHeath D SchmidtAshish P ThakrarHenry R KranzlerRenyu Liu
Published in: CNS neuroscience & therapeutics (2024)
Although dezocine is reinforcing in humans and monkeys with prior or concurrent opioid use within a restricted dose range, there are only a few anecdotal reports of dezocine abuse despite of the long history of use in humans. Given the evidence of dezocine's limited abuse potential, it could be useful both as a treatment for OUD. However, in-depth studies would be required for dezocine to be re-considered for clinical use.
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