SCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves.

Mian ZuWei-Wei GuoTao CongFei JiShi-Li ZhangYue ZhangXin SongWei SunDavid Z Z HeWei-Guo ShiShi-Ming Yang

Published in: BMC neuroscience (2021)

These data suggest a role of Nav1.9 in regulating the function of ribbon synapses and the auditory nerves. The impairment induced by Nav1.9 gene deletion mimics the characters of cochlear synaptopathy.

Keyphrases

hearing loss
copy number
working memory
genome wide
genome wide identification
electronic health record
big data
dna methylation
artificial intelligence
genome wide analysis
deep learning