Defiant: (DMRs: easy, fast, identification and ANnoTation) identifies differentially Methylated regions from iron-deficient rat hippocampus.

David E CondonPhu V TranYu-Chin LienJonathan SchugMichael K GeorgieffRebecca A SimmonsKyoung Jae Won

Published in: BMC bioinformatics (2018)

Defiant effectively identifies DMRs for whole-genome bisulfite sequencing (WGBS), reduced-representation bisulfite sequencing (RRBS), Tet-assisted bisulfite sequencing (TAB-seq), and HpaII tiny fragment enrichment by ligation-mediated PCR-tag (HELP) assays.

Keyphrases

single cell
genome wide
rna seq
high throughput
oxidative stress