Promoter Methylation of Two HOXA9 and NISCH Genes in Opium Users.
Majid MahmoodiFatemeh KaramiHamidreza AbdollahiNavidreza GiahiKouros DivsalarAmin HonarmandMohammad Hossein ModarressiPublished in: Addiction & health (2023)
genes as tumor suppressor in opium-addicted individuals can be considered as confirmatory evidence for carcinogenesis of opium. Further studies are required to figure out the role of epigenetic alterations in cancer evolution among opium users.