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Sex-specific alterations in cognitive control following moderate prenatal alcohol exposure and transient systemic hypoxia ischemia in the rat.

Brooke R DunnSarah L OlguinSuzy DaviesNathaniel G PavlikJonathan L BrigmanDerek HamiltonDaniel D SavageJessie R Maxwell
Published in: Alcohol, clinical & experimental research (2024)
Transient systemic hypoxia ischemia impaired performance on the 5C-CPT in females, leading to a bias toward stimulus responsivity regardless of stimulus type. In contrast, TSHI did not affect male offspring, and only slight effects of PAE were seen. Together, these data suggest that TSHI in females may cause alterations in cortical structures that override alterations caused by moderate PAE.
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