Upregulation of the canonical signaling pathway of interferon-gamma is associated with glioblastoma progression.

Sayra Ximena Zamora-SalasMarina Macías-SilvaAngeles C Tecalco-Cruz

Published in: Molecular biology reports (2024)

IFN-γ signaling pathway is upregulated in glioblastoma, displaying pro-tumor activity. Thus, IFN-γ signaling elements may be potential biomarkers and targets for treating glioblastoma.

Keyphrases

signaling pathway
dendritic cells
pi k akt
immune response
epithelial mesenchymal transition
induced apoptosis
cell proliferation